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Professor, Division of Endocrinology
Boyd Metzger, M.D. is the Tom D Spies Professor of Metabolism and Nutrition in the Division of Endocrinology, Metabolism & Molecular Medicine at Northwestern University Feinberg School of Medicine. Dr. Metzger obtained his undergraduate education at the University of South Dakota and earned his M.D. at the State University of Iowa. He was an Intern, Medical Resident and Clinical Fellow in Metabolism at Michael Reese Hospital in Chicago and a Postdoctoral Fellow in Biological Chemistry at Washington University in St Louis. Dr. Metzger's memberships in professional organizations include: the Endocrine Society, the American Diabetes Association (ADA), the American Federation for Medical Research, the Central Society for Clinical Investigation and American Association for the Advancement of Science (Fellow). Dr. Metzger has had a career-long interest in the impact of gestational diabetes pre existing diabetes and states of altered nutrition during pregnancy on the intrauterine, perinatal and lifelong health of offspring. He has served on the editorial board of Diabetes and of Diabetologia and has been a member of the Organizing Committee of each of the four ADA sponsored International Workshop Conferences on gestational diabetes mellitus (GDM) and Chairman and Proceedings Editor of the last two. He has published more than 200 journal articles and book chapters. Currently, he is Principal Investigator of the NICHD/NIDDK funded Hyperglycemia & Adverse Pregnancy Outcome (HAPO) study. The immediate objective of HAPO is to establish the level of maternal hyperglycemia that is associated with a clinically significant risk of adverse perinatal outcome. It is hoped that future risks for obesity and metabolic disturbances can also be established through long-term follow-up. Areas of Specialty - Gestational Diabetes Mellitus
- Lifelong Impact of Intrauterine Exposure to Maternal Diabetes
- Pathogenesis & Prevention of Type 2 Diabetes
View Faculty Profile Recent Journal Publications
Brickman WJ, Huang J, Silverman BL, Metzger BE. Acanthosis Nigricans Identifies Youth at High Risk for Metabolic Abnormalities. Journal Pediatrics 156:87-92, 2010.
Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study Cooperative Research Group (Metzger BE, HAPO Study PI). Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study: preeclampsia Am J Obstet Gynecol 202:255-57 (255.e1-7), 2010. Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study Cooperative Research Group (Metzger BE, HAPO Study PI). Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study: associations with body mass index. British J Obstet Gynecol 117:(5)575-84, 2010. International Association of Diabetes and Pregnancy Study Groups Recommendations on the diagnosis and classification of hyperglycemia in pregnancy (Metzger, BE, corresponding author). Diabetes Care 2010; 33(3):676-682. Ackerman CM, Lowe LP, Lee H, Chen F, Hughes E, Cholod P, Dyer AR, Hayes MG, Metzger BE, Lowe WL, Urbanek, M, for the HAPO Study Cooperative Research Group. The Role of the Polycystic Ovary Syndrome Susceptibility Locus D19S884 Allele 8 in Maternal Glycemia and Fetal Size. J Clin Endocrinol Metab 95(7):3242-3250,2010 (doi:10.1210/jc.2009-2718). HAPO Study Cooperative Research Group (Metzger BE, Study PI). Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study: Neonatal Glycemia. Pediatrics: 126(6): e1545-52, 2010(doi:10.1542/peds.2009-2257. Freathy RM, M. Hayes G, Urbanek M, Lowe LP, Lee H, Ackerman C, Frayling TM, Cox NJ, Dunger DB, Dyer AR, Hattersley AT, Metzger BE, Lowe WL, for the HAPO Study Cooperative Research Group. Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study: common genetic variants in GCK and TCF7L2 are associated with fasting and post-challenge glucose levels in pregnancy and with gestational diabetes as defined by the new IADPSG recommendations. Diabetes 59(10):2682-89, 2010. Lowe LP, PhD, Metzger BE, MD, Lowe WL Jr, Dyer AR, McDade TW, McIntyre, HD, for the HAPO Study Cooperative Research Group. Inflammatory Mediators and Glucose in Pregnancy: Results from a subset of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study. J Clin Endocrinol Metab 95(12):5427-34, 2010. Levy-Marchal C, Arslanian S, Cutfield W, Sinaiko A, Druet C, Marcovecchio ML, Chiarelli F. on behalf of ESPE-LWPES-ISPAD-APPES-APEG-SLEP-JSPE, and the Insulin Resistance in Children Consensus Conference Group (BE Metzger, member). J Clin Endocrinol Metab 95(12): 5189–5198, 2010). Yogev Y, Metzger BE, Hod M. Establishing diagnosis of gestational diabetes mellitus: Impact of the hyperglycemia and adverse pregnancy outcome study. Seminars in fetal & neonatal medicine. 2009;14(2):94-100.
PMID: 19211315
Kwak SH, Kim HS, Choi SH, Lim S, Cho YM, Park KS, Jang HC, Kim MY, Cho NH, Metzger BE
Subsequent Pregnancy after Gestational Diabetes Mellitus: Frequency and risk factors for recurrence in Korean women.
Diabetes care. 2008.
PMID: 18535194
Prevalence of type 2 diabetes among women with a previous history of gestational diabetes mellitus.
Lee H, Jang HC, Park HK, Metzger BE, Cho NH
Diabetes research and clinical practice. 2008.
PMID: 18456364
Hyperglycemia and adverse pregnancy outcomes.
HAPO Study Cooperative Research Group, Metzger BE, Lowe LP, Dyer AR, Trimble ER, Chaovarindr U, Coustan DR, Hadden DR, McCance DR, Hod M, McIntyre HD, Oats JJ, Persson B, Rogers MS, Sacks DA
The New England journal of medicine. 2008;358(19):1991-2002.
PMID: 18463375
Acanthosis nigricans: a common finding in overweight youth.
Brickman WJ, Binns HJ, Jovanovic BD, Kolesky S, Mancini AJ, Metzger BE, Pediatric Practice Research Group
Pediatric dermatology. 2007 Nov;24(6):601-6.
PMID: 18035980
Summary and recommendations of the Fifth International Workshop-Conference on Gestational Diabetes Mellitus.
Metzger BE, Buchanan TA, Coustan DR, de Leiva A, Dunger DB, Hadden DR, Hod M, Kitzmiller JL, Kjos SL, Oats JN, Pettitt DJ, Sacks DA, Zoupas C
Diabetes care. 2007;30 Suppl 2:S251-60.
PMID: 17596481
Visceral fatness and insulin sensitivity in women with a previous history of gestational diabetes mellitus.
Lim S, Choi SH, Park YJ, Park KS, Lee HK, Jang HC, Cho NH, Metzger BE
Diabetes care. 2007;30(2):348-53.
PMID: 17259506
Resting Heart Rate in Middle Age and Diabetes Development in Older Age.
Carnethon M, Yan L, Greenland P, Garside DB, Dyer AR, Metzger B, Daviglus ML
Diabetes care. 2007.
PMID: 17959868
Long-term Outcomes in Mothers Diagnosed With Gestational Diabetes Mellitus and Their Offspring.
Metzger BE
Clinical obstetrics and gynecology. 2007;50(4):972-9.
PMID: 17982340
Diet and medical therapy in the optimal management of gestational diabetes mellitus.
Metzger BE
Nestle Nutrition workshop series. Clinical & performance programme. 2006;11:155-65; discussion 165-9.
PMID: 16820738
Elevated homocysteine as a risk factor for the development of diabetes in women with a previous history of gestational diabetes mellitus: a 4-year prospective study.
Cho NH, Lim S, Jang HC, Park HK, Metzger BE
Diabetes care. 2005 Nov;28(11):2750-5.
PMID: 16249551
Declining insulin requirement in the late first trimester of diabetic pregnancy.
Jovanovic L, Knopp RH, Brown Z, Conley MR, Park E, Mills JL, Metzger BE, Aarons JH, Holmes LB, Simpson JL, National Institute of Child Health and Human Development Diabetes in Early Pregnancy Study Group
Diabetes care. 2001;24(7):1130-6.
PMID: 11423491
Correlations between the intrauterine metabolic environment and blood pressure in adolescent offspring of diabetic mothers.
Cho NH, Silverman BL, Rizzo TA, Metzger BE
The Journal of pediatrics. 2000;136(5):587-92.
PMID: 10802488
Recent Books and Book Chapters Wason CJ, Metzger BE. Diabetes Management for Mothers-To-Be. You Can Do It.. Tarrytown, NY: Bayer Corporation 2006, 1-46.
Metzger BE. American Medical Association: Guide to Preventing and Treating Type 2 Diabetes. Hoboken, NJ: John Wiley & Sons, Inc. 2006, 1-278.
Diabetes Care: Vol 30 (Suppl 2). In: BE Metzger (editor). Proceedings of the 5th International Workshop Conference on Gestational Diabetes Mellitus. Alexandria, VA: American Diabetes Association 2007, S105-S260.
72. Schmeltz L, Metzger B.. Diabetes/Syndrome X. In: DJ Triggle, JB Taylor. Comprehensive Medicinal Chemistry II, Vol 6. Oxford, UK: Elsevier 2006, 417-458.
Metzger B. Chapter 3. Gestational Diabetes Mellitus. In: D Gan. International Diabetes Federation, Diabetes Atlas, Third Edition. Brussels, Belgium: Hoorens Printing NV, Belgium 2006, 211-15.
Metzger B.. Gestational Diabetes Mellitus. In: D Gan. International Diabetes Federation, Diabetes Atlas 2000. Brussels, Belgium: Imprimerie L Vanmelle SA, Gent/Mariakerke 2000, 236-39.
Metzger BE. The Freinkel Legacy. In: Hod M, Jovanovic L, Di Renzo GC, de Leiva A, Langer O. Textbook of Diabetes and Pregnancy, Second Edition . London: Informa UK Ltd 2008, 19-24.
Metzger BE, Kim YL. Detection And Diagnostic Strategies For Gestational Diabetes Mellitus. In: Hod M, Jovanovic L, Di Renzo GC, de Leiva A, Langer O. Textbook of Diabetes and Pregnancy, Second Edition. London: Informa UK Ltd 2008, 156-164.
Metzger BE, Kim YL. Detection And Diagnostic Strategies For Gestational Diabetes Mellitus. In: Hod M, de Leiva A, Jovanovic L et al. Eds. Textbook of Diabetes and Pregnancy. London: Martin Dunitz, Taylor and Francis Group 2003, 168-182.
Metzger BE, Phelps RL, Dooley SL. The Mother in Pregnancies Complicated by Diabetes Mellitus. In: Silvio E. Inzucchi, Daniel Porte, Jr., Robert S. Sherwin, Alain Baron Eds.. The Diabetes Mellitus Manual. A primary care compendium to Ellenberg and Rifkin's, 6th Edition. New York, NY: McGraw-Hill 2004, 202-220.
Metzger BE, Phelps RL, Dooley SL. The Mother in Pregnancies Complicated by Diabetes Mellitus. In: Daniel Porte, Jr., Robert S Sherwin, Alain Baron. Ellenberg & Rifkins Diabetes Mellitus, 6th edition. New York, NY: McGraw-Hill 2003, 619-40.
Metzger BE, Prurdy LP, Phelps RL. Diabetes Mellitus and Pregnancy. In: Leslie J DeGroot, J Larry Jameson, Henry Burger, et al. Eds. Endocrinology, 4th Edition. Philadelphia, PA: W. B. Saunders Co. 2001, 2433-45.
Metzger BE, Purdy LP, Phelps RL. Diabetes Mellitus and Pregnancy. In: LJ DeGroot, JL Jameson, Sr editors. Endocrinology, 5th Editiion. Philadelphia, PA: Elsevier Saunders 2006, 3419-3435.
Metzger Boyd E, Cho Nam H, Brickman Wendy J. The Rising Tide of Diabetes Mellitus: Implications for Women of All Ages. In: E Albert Reece, Donald R Coustan, Steven G Gabbe. Diabetes In Women, 3rd edition. Philadelphia, PA: Lippincott Williams & Wilkins 2004, 9-26.
Metzger, BE. Forward. In: Hod M, Jovanovic L, Di Renzo GC, de Leiva A, Langer O. Textbook of Diabetes and Pregnancy, Second Edition. London: Informa UK Ltd 2008, XV.
Metzger, BE. Foreword. In: Hod M, de Leiva A, Jovanovic L et al. Eds. Textbook of Diabetes and Pregnancy. London: Martin Dunitz, Taylor and Francis Group 2003, vii.
Metzger, BE. The Freinkel Legacy. In: Hod M, de Leiva A, Jovanovic L et al. Eds. Textbook of Diabetes and Pregnancy. London: Martin Dunitz, Taylor and Francis Group 2003, 30-38.
Purdy LP, Metzger, BE.. Medical Management of Diabetes in Pregnancy. In: JK Davidson. Clinical Diabetes Mellitus, A Problem Oriented Approach, 3rd Edition. New York: Thieme 2000, 685-704.
Purdy LP, Metzger BE.. Endocrine Problems in Pregnancy. In: ME Molitch. Challenging Cases in Endocrinology. Totowa, NJ: Humana Press 2002, 269-85.
Silverman BL, Ogata ES, Metzger BE. The Offspring of the Mother With Diabetes. In: Silvio E Inzucchi, Daniel Porte, Jr., Robert S. Sherwin, Alain Baron Eds.. The Diabetes Mellitus Manual. A primary care compendium to Ellenberg and Rifkin's, 6th Edition. New York, NY: McGraw-Hill 2004, 221-230.
Silverman BL, Ogata ES, Metzger BE. The Offspring of the Mother With Diabetes. In: Daniel Porte, Jr., Robert S Sherwin, Alain Baron. Ellenberg & Rifkins Diabetes Mellitus, 6th edition. New York, NY: McGraw-Hill 2003, 641-51. |
