Cardiovascular Complications of Obesity

Obesity, particularly central obesity, is a major risk factor for the development of hypertension and an important independent risk for coronary artery disease. It is estimated that at least 75% of “essential” hypertension is related to obesity. The pathogenesis of obesity related hypertension involves insulin resistance and associated lipid abnormalities which, in conjunction with the elevated blood pressure, is known as the “metabolic syndrome.” This syndrome carries with it an enhanced risk of myocardial infarction, stroke and congestive heart failure.